Neurodevelopment After Neonatal Acute Kidney Injury in Very Preterm-Birth Children

IntroductionTo assess head circumference (HC) growth and neurodevelopmental outcomes in very preterm-birth children after neonatal AKI.MethodsThis longitudinal follow-up cohort included 732 preterm neonates of gestational age <31 weeks admitted to a tertiary center between 2008 2020. AKI was categorized as non-oliguric oliguric based on the urine-output criteria during admission. We compared differences death, z scores HC (zHC) at term-equivalent (TEA) corrected 6, 12, 24 months, months AKI.ResultsAmong 154 who developed AKI, 72 had 82 AKI. At TEA, but not independently associated with lower zHC than non-AKI (mean differences, -0.49; 95% confidence interval [CI], -0.92∼ -0.06). Although three groups were comparable ages group higher rate microcephaly by months. Additionally, group, more likely die (61% vs. 9%) have impairment (41% 14%) group. After adjustment, (adjusted odds ratio [aOR], 8.97; CI, 2.19∼36.76) impairment.ConclusionsNeonatal is children. Long-term head-size warranted.